KIF14 antibody (Kinesin Family Member 14)

Details for Product anti-KIF14 Antibody No. ABIN6566849
Antigen
Reactivity
Human
37
15
15
1
Host
Rabbit
35
2
Clonality
Polyclonal
Conjugate
This KIF14 antibody is un-conjugated
4
3
2
2
2
2
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
18
10
10
8
8
6
5
4
2
1
1
Options
Immunogen Recombinant protein of human KIF14
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name KIF14 (KIF14 Antibody Abstract)
Background

Synonyms: KIAA0042,KIF 14,KIF14,KIF14,Kinesin Family Member 14,Kinesin like protein KIF14,Kinesin-like protein KIF14,MGC142302

Background: This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. In human HeLa-S3 and 293T cells, this protein is localized to the cytoplasm during interphase, to the spindle poles and spindle microtubules during mitosis, and to the midbody during cytokinesis. An internal motor domain displays microtubule-dependent ATPase activity, consistent with its function as a microtubule motor protein. Knockdown of this gene results in failed cytokinesis with endoreplication, which results in multinucleated cells. This gene has been identified as a likely oncogene in breast, lung and ovarian cancers, as well as retinoblastomas and gliomas. Alternative splicing results in multiple transcript variants.

Molecular Weight

Observed_MW: 190kDa

Calculated_MW: 186kDa

Gene ID 9928
UniProt Q15058
Application Notes WB 1:1000 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Kinesin Family Member 14 (KIF14) antibody (ABIN6566849) Western blot analysis of extracts of various cell lines, using KIF14 antibody.