Synonyms: 2700049B16Rik,3110031N04Rik,BK channel subunit beta 2,BK channel subunit beta-2,BKbeta2,Calcium activated potassium channel subfamily M subunit beta 2,Calcium activated potassium channel subunit beta 2,Calcium-activated potassium channel,Calcium-activated potassium channel subunit beta-2,Charybdotoxin receptor subunit beta 2,Charybdotoxin receptor subunit beta-2,Hbeta2,Hbeta3,K(VCA)beta-2,K(VCA)beta2,KCMB2,KCNMB 2,Kcnmb2,Large conductance Ca2+ activated K+ channel beta2 subunit,Large conductance calcium activated potassium channel beta 2 subunit,Maxi K channel subunit beta 2,Maxi K channel subunit beta-2,MaxiK channel beta 2 subunit,MGC22431,MGC57945,Potassium large conductance calcium activated channel subfamily M beta member 2,Slo-beta-2,Slobeta2,subfamily M subunit beta-2
Background: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described.