CD276 antibody (CD276 Molecule)

Details for Product anti-CD276 Antibody No. ABIN6566887
Antigen
Reactivity
Human
120
51
31
3
3
3
2
2
2
2
Host
Rabbit
65
62
18
1
Clonality
Polyclonal
Conjugate
This CD276 antibody is un-conjugated
8
7
5
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Western Blotting (WB)
70
68
47
22
20
13
11
9
5
2
2
2
1
1
1
Options
Immunogen A synthetic peptide of human CD276
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name CD276 (CD276 Antibody Abstract)
Background

Synonyms: 4Ig B7 H3,4Ig-B7-H3,AU016588,B7 H3,B7 homolog 3,B7-H3,B7H3,B7RP-2,CD_antigen=CD276,CD276,CD276 antigen,CD276 Molecule,CD276,Costimulatory molecule,Flags: Precursor,PSEC0249,UNQ309/PRO352

Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight

Observed_MW: 115kDa

Calculated_MW: 33kDa/52kDa/57kDa

Gene ID 80381
UniProt Q5ZPR3
Pathways Cancer Immune Checkpoints
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-CD276 Molecule (CD276) antibody (ABIN6566887) Western blot analysis of extracts of various cell lines, using CD276 antibody.