PLOD3 antibody (Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3)

Details for Product anti-PLOD3 Antibody No. ABIN6566977
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
44
9
8
Host
Rabbit
39
5
Clonality
Polyclonal
Conjugate
This PLOD3 antibody is un-conjugated
3
3
2
2
2
2
Application
Western Blotting (WB)
43
25
13
5
2
2
2
1
1
Options
Immunogen Recombinant protein of human PLOD3
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name PLOD3 (PLOD3 Antibody Abstract)
Background

Synonyms: 2-oxoglutarate 5-dioxygenase 3,bone protein I,BP-I,LH3,Lysine hydroxylase 3,Lysyl hydroxylase 3,Plod3,PLOD3,Procollagen lysine,2 oxoglutarate 5 dioxygenase 3 precursor,Procollagen-lysine

Background: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity.

Molecular Weight

Observed_MW: 80kDa

Calculated_MW: 84kDa

Gene ID 8985
UniProt O60568
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3) antibody (ABIN6566977) Western blot analysis of extracts of various cell lines, using PLOD3 antibody.