PLOD3 antibody (N-Term)
Quick Overview for PLOD3 antibody (N-Term) (ABIN656661)
Target
See all PLOD3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 78-105, N-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This PLOD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-105 amino acids from the N-terminal region of human PLOD3.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- PLOD3 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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Expiry Date
- 6 months
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- PLOD3 (Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3))
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Alternative Name
- PLOD3
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Background
- The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity.
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Molecular Weight
- 84785
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Gene ID
- 8985
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NCBI Accession
- NP_001075
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UniProt
- O60568
Target
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