Cadherin 4 antibody (CDH4)

Details for Product anti-CDH4 Antibody No. ABIN6566983
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
95
45
27
2
2
2
2
1
1
Host
Rabbit
80
15
2
Clonality
Polyclonal
Conjugate
This Cadherin 4 antibody is un-conjugated
7
6
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Western Blotting (WB)
70
40
36
26
22
14
13
8
5
2
Options
Immunogen Recombinant protein of human CDH4
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name R-Cadherin (CDH4 Antibody Abstract)
Background

Synonyms: CADH4,Cadherin 4,Cadherin-4,cdh4,R CAD,R-CAD,R-cadherin,Retinal cadherin

Background: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.

Molecular Weight

Observed_MW: 100kDa

Calculated_MW: 92kDa/100kDa

Gene ID 1002
UniProt P55283
Pathways Cell-Cell Junction Organization, Regulation of Cell Size
Application Notes WB 1:1000 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Cadherin 4 (CDH4) antibody (ABIN6566983) Western blot analysis of extracts of various cell lines, using CDH4 antibody.