Synonyms: epididymis secretory protein Li 95,HEL-S-95,Mammalian STE20 like protein kinase 3,Mammalian STE20-like protein kinase 3,Mammalian STE20-like protein kinase 3 C-terminal,Mammalian STE20-like protein kinase 3 N-terminal,Mammalian sterile 20-like 3,MST-3,MST3/C,MST3/N,MST3B,serine threonine kinase 24,Serine/threonine kinase 24 (Ste20,yeast homolog),Serine/threonine-protein kinase 24 12 kDa subunit,Serine/threonine-protein kinase 24,STE20 homolog yeast,STE20 like kinase MST3,STE20-like kinase MST3,Stk24,STK24,STK3
Background: This gene encodes a serine/threonine protein kinase that functions upstream of mitogen-activated protein kinase (MAPK) signaling. The encoded protein is cleaved into two chains by caspases, the N-terminal fragment (MST3/N) translocates to the nucleus and promotes programmed cells death. There is a pseudogene for this gene on chromosome X. Alternative splicing results in multiple transcript variants.