STK24 antibody (N-Term)

Catalog No. ABIN6259111

Product Details anti-STK24 Antibody

Target: STK24 (serine/threonine Kinase 24 (STK24))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK24 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: MST3 Antibody detects endogenous levels of total MST3.

Predicted Reactivity: Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MST3, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for STK24

Target: STK24 (serine/threonine Kinase 24 (STK24))

Alternative Name: STK24 (STK24 Products)

Synonyms: MST3 antibody, MST3B antibody, STE20 antibody, STK3 antibody, 1810013H02Rik antibody, C76483 antibody, MST-3 antibody, Mst3 antibody, Mst3b antibody, RGD1561742 antibody, stk24 antibody, wu:fi29b08 antibody, zgc:66137 antibody, 0610042I06Rik antibody, MST antibody, Mst2 antibody, Ste20 antibody, mess1 antibody, zgc:163071 antibody, mst3 antibody, mst3b antibody, ste20 antibody, stk3 antibody, serine/threonine kinase 24 antibody, serine/threonine kinase 24b (STE20 homolog, yeast) antibody, serine/threonine-protein kinase 24 antibody, serine/threonine kinase 3 antibody, serine/threonine kinase 24a (STE20 homolog, yeast) antibody, serine/threonine kinase 24 L homeolog antibody, STK24 antibody, Stk24 antibody, stk24b antibody, ATEG_04314 antibody, ATEG_09179 antibody, UREG_03984 antibody, BDBG_07988 antibody, MCYG_07323 antibody, Stk3 antibody, stk24a antibody, stk24.L antibody

Background:

Description: Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. In association with STK26 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation (PubMed:27807006). Regulates also cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.

Gene: STK24

Molecular Weight: 50 kDa

Gene ID: 8428

UniProt: Q9Y6E0