Lipocalin 2 (LCN2) antibody

Details for Product No. ABIN6567067
Antigen
Reactivity
Human
255
85
78
13
8
2
1
Host
Rabbit
219
100
12
11
4
1
Clonality
Polyclonal
Conjugate
Un-conjugated
52
26
15
6
6
6
6
6
6
2
2
2
2
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
232
203
101
34
16
13
12
11
10
9
7
5
4
3
2
2
2
2
2
2
1
1
1
1
Options
Immunogen Recombinant protein of human LCN2
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name LCN2 (LCN2 Antibody Abstract)
Background

Synonyms: 24p3,25 kDa alpha 2 microglobulin related subunit of MMP9,25 kDa alpha-2-microglobulin-related subunit of MMP-9,Alpha 2 microglobulin related protein,HGNC:6526,HNL,Lcn 2,Lcn2,Lipocalin-2,Migration stimulating factor inhibitor,MSFI,Neutrophil gelatinase associated lipocalin,Neutrophil gelatinase associated lipocalin precursor,Neutrophil gelatinase-associated lipocalin,NGAL,NGAL,Oncogene 24p3,Oncogenic lipocalin 24p3,p25,Siderocalin,siderocalin LCN2,SV40 induced 24P3 protein,Uterocalin

Background: This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.

Molecular Weight

Observed_MW: 23kDa

Calculated_MW: 22kDa

Gene ID 3934
UniProt P80188
Pathways Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis
Application Notes WB 1:500 - 1:2000 IF 1:10 - 1:100
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Lipocalin 2 (LCN2) antibody (ABIN6567067) Western blot analysis of extracts of A-549 cells, using LCN2 antibody.
Image no. 2 for anti-Lipocalin 2 (LCN2) antibody (ABIN6567067) Immunofluorescence analysis of A549 cells using LCN2 antibody.