Claudin 7 antibody

Catalog No. ABIN6569064

Product Details anti-Claudin 7 Antibody

Target: Claudin 7 (CLDN7)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 7 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human CLDN7

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Claudin 7

Target: Claudin 7 (CLDN7)

Alternative Name: Claudin 7 (CLDN7 Products)

Background:

Synonyms: CEPTR L2,CEPTRL 2,CEPTRL2,Claudin 1,Claudin 9,Claudin-7,Claudin1,Claudin7,Claudin9,CLD7,CLDN 7,CLDN-7,CLDN7,Clostridium perfringens enterotoxin receptor like 2,CPETR L2,CPETRL 2,CPETRL2,Hs.84359

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.

Molecular Weight:

Observed_MW: 29kDa

Calculated_MW: 16kDa/22kDa

Gene ID: 1366

UniProt: O95471

Pathways: Hepatitis C