Claudin 7 antibody (C-Term)

Catalog No. ABIN951552

The Rabbit Polyclonal anti-Claudin 7 antibody (ABIN951552) specifically detects Claudin 7 in WB, FACS, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for Claudin 7 antibody (C-Term) (ABIN951552)

Target: Claudin 7 (CLDN7)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 7 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Claudin 7 Antibody

Binding Specificity: AA 179-209, C-Term

Specificity: This antibody reacts to CLDN7.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 179-209 amino acids from the C-terminal region of human CLDN7

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Claudin 7

Target: Claudin 7 (CLDN7)

Alternative Name: Claudin-7 / CLDN7

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.Synonyms: CEPTRL2, CLDN-7, CPETRL2

Molecular Weight: 22418 Da

Gene ID: 1366

NCBI Accession: NP_001171951

Pathways: Hepatitis C