SH3GL1 antibody

Catalog No. ABIN6571145

Product Details anti-SH3GL1 Antibody

Target: SH3GL1 (SH3-Domain GRB2-Like 1 (SH3GL1))

Reactivity: Human, Rat, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3GL1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human SH3GL1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SH3GL1

Target: SH3GL1 (SH3-Domain GRB2-Like 1 (SH3GL1))

Alternative Name: SH3GL1 (SH3GL1 Products)

Background:

Synonyms: CNSA1,EEN,EEN fusion partner of MLL,Endophilin-2,Endophilin-A2,Extra 11 19 leukemia fusion gene ,Extra eleven-nineteen leukemia fusion gene protein,Fusion partner of MLL,MGC111371,SH3 containing Grb 2 like 1 protein,SH3 containing protein EEN,SH3 domain GRB2 like 1,SH3 domain protein 2B,SH3 domain-containing GRB2-like protein 1,SH3D2B,SH3G1,Sh3gl1,SH3P8

Background: This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight:

Observed_MW: 41kDa

Calculated_MW: 34kDa/36kDa/41kDa

Gene ID: 6455

UniProt: Q99961