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ITGA2 antibody (Integrin alpha 2) Primary Antibody

ITGA2 Reactivity: Human, Mouse, Rat IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6571242
$438.90
Plus shipping costs $45.00
200 μL ABIN6571242
200 μL ABIN6571242
local_shipping Shipping to: United States
Delivery in 9 to 11 Business Days
  • Target
    ITGA2
    Reactivity
    Human, Mouse, Rat
    • 157
    • 68
    • 20
    • 14
    • 10
    • 10
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    This ITGA2 antibody is un-conjugated
    • 79
    • 28
    • 23
    • 18
    • 10
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunohistochemistry (IHC), Western Blotting (WB)
    • 98
    • 85
    • 59
    • 45
    • 15
    • 15
    • 13
    • 12
    • 10
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human ITGA2
    Isotype
    IgG
  • Application Notes
    WB 1:500 - 1:2000 IHC 1:100 - 1:200
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ITGA2
    Alternative Name
    ITGA2 (ITGA2 Antibody Abstract)
    Synonyms
    BR, CD49B, GPIa, HPA-5, VLA-2, VLAA2, DX5, integrin subunit alpha 2, integrin alpha 2, ITGA2, Itga2
    Background

    Synonyms: BR,CD 49b,CD49 antigen like family member B,CD49 antigen-like family member B,CD49b,CD49b antigen,Collagen receptor,DX5,Glycoprotein Ia deficiency included,GP Ia,GP Ia deficiency,included,GPIa,HPA 5 included,HPA5 included,Human platelet alloantigen system 5,Integrin alpha 2,Integrin alpha II,Integrin alpha-2,Integrin,alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor),ITA2,ITGA2,Platelet alloantigen Br(a),included,Platelet antigen Br,Platelet glycoprotein GPIa,Platelet glycoprotein Ia,Platelet glycoprotein Ia/IIa,Platelet membrane glycoprotein Ia,Platelet receptor for collagen,deficiency of,included,Very late activation protein 2 receptor alpha 2 subunit,VLA 2 alpha chain,VLA 2,VLA 2 subunit alpha,VLA-2 subunit alpha,VLA2,VLA2 receptor alpha 2 subunit,VLAA2

    Background: This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

    Molecular Weight

    Observed_MW: 150kDa

    Calculated_MW: 129kDa

    Gene ID
    3673
    UniProt
    P17301
    Pathways
    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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