EHMT1 antibody

Catalog No. ABIN6571811

The Rabbit Polyclonal anti-EHMT1 antibody has been validated for WB. It is suitable to detect EHMT1 in samples from Human, Mouse and Rat.

Quick Overview for EHMT1 antibody (ABIN6571811)

Target: EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EHMT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EHMT1 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human EHMT1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EHMT1

Target: EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))

Alternative Name: EHMT1

Background:

Synonyms: bA188C12.1,DKFZp667M072,EHMT 1,EHMT1,EHMT1,Eu-HMTase1,Euchromatic histone lysine N methyltransferase 1,Euchromatic histone methyltransferase 1,Euchromatic histone-lysine N-methyltransferase 1,EUHMTASE1,FLJ12879,FP13812,G9a like protein 1,G9a like protein,G9a-like protein 1,GLP 1,GLP,GLP1,H3 K9 HMTase 5,H3-K9-HMTase 5,Histone H3 K9 methyltransferase 5,Histone H3-K9 methyltransferase 5,Histone lysine N methyltransferase H3 lysine 9 specific 5,Histone-lysine N-methyltransferase EHMT1,KIAA1876,Lysine N methyltransferase 1D,Lysine N-methyltransferase 1D,RP11 188C12.1

Background: The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 141kDa

Calculated_MW: 7kDa/86kDa/128kDa/141kDa

Gene ID: 79813

UniProt: Q9H9B1