CACNA1H antibody (Internal Region)

Catalog No. ABIN6656950

Supplier Product No.: 200-301-f11

Product Details anti-CACNA1H Antibody

Target: CACNA1H (Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H))

Binding Specificity: Internal Region

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CACNA1H antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Fluorescence Microscopy (FM)

Supplier Product No.: 200-301-f11

Supplier: Rockland

Purpose: CAV3.2 Antibody

Purification: Anti-CAV3.2 Antibody was purified by Protein G chromatography.

Sterility: Sterile filtered

Immunogen: Cav3.2 Antibody was produced in mice by repeated immunizations with a fusion protein corresponding to an internal region (II-III loop) of human Cav3.2.

Clone: N55-10

Isotype: IgG1

Application Details

Application Notes:

Immunoprecipitation_Dilution: User Optimized

Immunohistochemistry_Dilution: 0.1-1.0 μg/mL

IF_Microscopy_Dilution: 1.0-10 μg/mL

Western_Blot_Dilution: 1-10 μg/mL

Comment:

Anti-CAV3.2 Antibody is tested by WB, IP, IHC, and IF microscopy. Expect a band approximately ~260kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.09 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for CACNA1H

Target: CACNA1H (Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H))

Alternative Name: CAV3.2 (CACNA1H Products)

Background:

Synonyms: CACNA1HB, Alpha1 3.2, CACNA 1H, CACNA1 HB, Cav T.2, EIG6, Voltage dependent T type calcium channel alpha 1H, Low-voltage-activated calcium channel alpha1 3.2 subunit, Voltage-gated calcium channel subunit alpha Cav3.2

Background: Specifically, Cav3.2 is a protein which in humans is encoded by the CACNA1H gene. Studies suggest certain mutations in this gene lead to childhood absence epilepsy. Studies also suggest that the up-regulations of Cav3.2 may participate in the progression of prostate cancer toward an androgen-independent stage.

Gene Name: CACNA1H

Gene ID: 8912

NCBI Accession: NP_001005407

UniProt: O95180

Pathways: C21-Steroid Hormone Metabolic Process