KCND3 antibody (C-Term)

Catalog No. ABIN6658138

Supplier Product No.: 200-301-g04

Product Details anti-KCND3 Antibody

Target: KCND3 (Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3))

Binding Specificity: C-Term

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This KCND3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Supplier Product No.: 200-301-g04

Supplier: Rockland

Purpose: Kv4.3 K+ channel Antibody

Purification: Anti-Kv4.3 Antibody was purified by Protein G chromatography.

Sterility: Sterile filtered

Immunogen: Kv4.3 K+ channel Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding to cytoplasmic C-terminus region of rat Kv4.3.

Clone: S75-41

Isotype: IgG1

Application Details

Application Notes:

Immunoprecipitation_Dilution: User Optimized

Immunohistochemistry_Dilution: 0.1-1.0 μg/mL

IF_Microscopy_Dilution: 1.0-10 μg/mL

Western_Blot_Dilution: 1 μg/mL

Comment:

Anti-Kv4.3 Antibody is tested for use in WB, IP, and IHC. Expect a band approximately ~75kDa in rat brain membrane preparations. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.09 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for KCND3

Target: KCND3 (Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3))

Alternative Name: Kcnd3 (KCND3 Products)

Background:

Synonyms: Kv4.3, Kcnd3, Potassium voltage-gated channel subfamily D member 3, Voltage-gated potassium channel subunit Kv4.3

Background: Potassium voltage-gated channel subfamily D member 3 (also known as Kv4.3) is a protein that in humans is encoded by the KCND3 gene. It contributes to the cardiac transient outward potassium current, the main contributing current to the repolarizing phase 1 of the cardiac action potential.

Gene Name: Kcnd3

Gene ID: 65195

NCBI Accession: NP_113927

UniProt: Q62897