SLC6A13 antibody (C-Term)

Catalog No. ABIN6658282

Supplier Product No.: 612-401-d57

Product Details anti-SLC6A13 Antibody

Target: SLC6A13 (Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 13 (SLC6A13))

Binding Specificity: C-Term

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC6A13 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Supplier Product No.: 612-401-d57

Supplier: Rockland

Purpose: GABA Transporter 2 (GAT2) Antibody

Cross-Reactivity (Details): Anti-GAT2 antibody is directed against rat GAT2 protein.

Purification: GABA Transporter 2 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: Anti-GABA Transporter 2 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry_Dilution: 1:100-200

Western_Blot_Dilution: 1:100-200

Comment:

Anti-GAT2 (Rabbit) Antibody is tested for use in WB and IHC. Specific conditions for reactivity should be optimized by the end user. GAT2 antibody is specific for the approximately 82 kDa in size GABA Transporter 2 protein.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for SLC6A13

Target: SLC6A13 (Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 13 (SLC6A13))

Alternative Name: GABA Transporter 2 (GAT2) (SLC6A13 Products)

Background:

Synonyms: Sodium- and chloride-dependent GABA transporter 2, Solute carrier family 6 member 13

Background: GAT2 Antibody detects rat GAT2 protein. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex. Anti-GAT2 Antibody is ideal for investigators involved in Neuroscience.

Gene Name: SLC6A13

Gene ID: 171163

NCBI Accession: NP_598307

UniProt: P31646