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SLC6A13 antibody (Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 13) (C-Term) Primary Antibody

SLC6A13 Reactivity: Rat IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6658282
$375.00
Plus shipping costs $45.00 and $24.00 dry ice
100 μL
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  • Target
    SLC6A13
    Binding Specificity
    • 8
    • 4
    • 2
    • 1
    • 1
    C-Term
    Reactivity
    • 18
    • 16
    • 15
    • 1
    Rat
    Host
    • 24
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC6A13 antibody is un-conjugated
    Application
    • 14
    • 11
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    Purification
    Anti-GAT2 antibody is directed against rat GAT2 protein. GABA Transporter 2 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected from the following species based on 100% sequence homology: mouse.
    Immunogen

    Immunogen: Anti-GABA Transporter 2 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.

    Immunogen Type: Peptide

    Isotype
    IgG
  • Application Notes

    Immunohistochemistry Dilution: 1:100-200

    Application Note: Anti-GAT2 (Rabbit) Antibody is suitable for use in IHC. This antibody is not recommended for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. GAT2 antibody is specific for the approximately 82 kDa in size GABA Transporter 2 protein.

    Western Blot Dilution: not recommended

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    Storage
    4 °C,-20 °C
    Storage Comment
    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
  • Target
    SLC6A13
    Alternative Name
    GABA Transporter 2 (GAT2) (SLC6A13 Antibody Abstract)
    Synonyms
    GAT3, Gabt3, Gat2, GAT-2, GAT2, solute carrier family 6 (neurotransmitter transporter, GABA), member 13, solute carrier family 6 member 13, Slc6a13, SLC6A13
    Background

    Synonyms: Sodium- and chloride-dependent GABA transporter 2, Solute carrier family 6 member 13

    Background: GAT2 Antibody detects rat GAT2 protein. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex. Anti-GAT2 Antibody is ideal for investigators involved in Neuroscience.

    Gene Name: SLC6A13

    Gene ID
    171163
    NCBI Accession
    NP_598307
    UniProt
    P31646
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