Nuclear Stain of Multiple Gene Products Including Nup62, Nup133 antibody
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- Target
- Nuclear Stain of Multiple Gene Products Including Nup62, Nup133
- Reactivity
- Saccharomyces cerevisiae
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- Un-conjugated
- Application
- Immunofluorescence (IF), Fluorescence Microscopy (FM)
- Supplier Product No.
- 900-301-d98
- Supplier
- Rockland
- Purpose
- Nuclear Pore Complex Antibody
- Cross-Reactivity (Details)
- Anti-Nuclear Pore Complex antibody is directed against Nuclear Pore Complex proteins.
- Purification
- The antibody is protein G purified from concentrated clarified cell culture supernate.
- Immunogen
- Anti-Nuclear Pore Complex Antibody (Monoclonal) was produced by repeated immunizations with yeast nuclear preparations.
- Clone
- 39C7
- Isotype
- IgG1
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anti-Nuclear Stain of Multiple Gene Products Including Nup62, Nup133 antibody
Reactivity: Saccharomyces cerevisiae IF Host: Mouse Monoclonal 39C7 unconjugated
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- Application Notes
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IF_Microscopy_Dilution: 1:50-100
Other: User Optimized
- Comment
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Anti-Nuclear Pore Complex Antibody is tested for use in ICC/IF. Specific conditions for reactivity should be optimized by the end user
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 ,0.01 % (w/v) Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
- Expiry Date
- 12 months
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- Target
- Nuclear Stain of Multiple Gene Products Including Nup62, Nup133
- Background
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Synonyms: mouse anti-Nuclear Pore Complex Antibody, NPC, NUP62, NUP, NUP133
Background: Nuclear Pore Complex Antibodydetects Nuclear Pore Complex proteins. The nuclear pore complex (NPC) is a very large structure made up of at least 50 different proteins that span the double membrane of the nuclear envelope functioning as a gateway for macromolecular traffic between the cytoplasm and the nucleus. Discrete nuclear pore complex proteins or nucleoporins such as NUP98, NUP180 and p62 have been implicated in autoimmune disease and cancer. Patients with primary biliary cirrhosis (PBC) frequently produce autoantibodies against p62 and NUP180 while NUP98 translocations have been found in patients with acute myelogenous leukemia (AML). Anti-Nuclear Pore Complex Antibody is ideal for investigators involved in Cancer and Immunology Research.
Gene Name: Nuclear stain of multiple gene products including Nup62, Nup133
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