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TUBB3 antibody

TUBB3 Reactivity: Rat WB, IHC Host: Mouse Monoclonal AA10 unconjugated
Rockland
Catalog No. ABIN6699201
Supplier Product No.: 212-301-e55
  • Target See all TUBB3 Antibodies
    TUBB3 (Tubulin, beta 3 (TUBB3))
    Reactivity
    • 127
    • 73
    • 65
    • 21
    • 9
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Rat
    Host
    • 81
    • 50
    • 4
    • 1
    • 1
    Mouse
    Clonality
    • 73
    • 64
    Monoclonal
    Conjugate
    • 78
    • 13
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TUBB3 antibody is un-conjugated
    Application
    • 105
    • 43
    • 40
    • 34
    • 28
    • 24
    • 20
    • 15
    • 15
    • 14
    • 14
    • 6
    • 5
    • 4
    • 4
    Western Blotting (WB), Immunohistochemistry (IHC)
    Supplier Product No.
    212-301-e55
    Supplier
    Rockland
    Purpose
    Tubulin beta 3 Antibody
    Cross-Reactivity (Details)
    Anti-Tubulin beta 3 Antibody is directed against rat Tubulin beta III protein.
    Purification
    The antibody was Protein G purified from cell culture supernatant.
    Immunogen
    Anti-Tubulin beta 3 Monoclonal Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues specific to beta III tubulin.
    Clone
    AA10
    Isotype
    IgG
    Top Product
    Discover our top product TUBB3 Primary Antibody
  • Application Notes

    Immunohistochemistry_Dilution: 1:1,000

    Western_Blot_Dilution: 1:10,000

    Other: User Optimized

    Comment

    Anti-Tubulin beta 3 (Mouse) antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 55 kDa in size corresponding to beta III tubulin proteins in the appropriate cell lysate or extract.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    Storage
    4 °C,-20 °C
    Storage Comment
    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
    Expiry Date
    12 months
  • Target
    TUBB3 (Tubulin, beta 3 (TUBB3))
    Alternative Name
    Tubulin beta 3 (TUBB3 Products)
    Background

    Synonyms: mouse anti-Tubulin beta 3 Antibody, Neuron-specific class III beta-tubulin, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III

    Background: Tubulin beta 3 Antibody detects Tubulin beta III protein. Tubulin is the major constituent of microtubules, existing as a heterodimer of the α and β subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins. Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy.

    Gene Name: TUBB3

    Gene ID
    246118
    UniProt
    Q4QRB4
    Pathways
    Microtubule Dynamics, M Phase
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