PD-1 antibody (Programmed Cell Death 1) (PE-Cy5.5)

Details for Product anti-PDCD1 Antibody No. ABIN6727399
Antigen
  • CD279
  • PD-1
  • PD1
  • SLEB2
  • hPD-1
  • hPD-l
  • Ly101
  • Pdc1
  • programmed cell death 1
  • PDCD1
  • Pdcd1
Reactivity
Mouse (Murine)
373
144
51
5
3
1
Host
Rat
196
174
35
24
17
11
5
4
2
Clonality (Clone)
Monoclonal ()
Conjugate
This PD-1 antibody is conjugated to PE-Cy5.5
29
21
20
12
8
7
5
5
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
246
180
131
111
95
71
26
15
15
13
12
11
10
10
9
5
4
4
2
2
Options
Clone 29F-1A12
Isotype IgG2a, kappa
Plasmids, Primers & others Plasmids, Primers & others PD-1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CD279/PD-1 (PDCD1 Antibody Abstract)
Background

Synonyms: PD-1, Programmed Death-1

Background: CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

Gene ID 18566
UniProt Q02242
Pathways Cancer Immune Checkpoints
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS with 0.05 % Proclin300, 1 % BSA
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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