NCR1 antibody (Natural Cytotoxicity Triggering Receptor 1) (APC)

Details for Product anti-NCR1 Antibody No. ABIN6728289
Target
Reactivity
Mouse
66
38
18
6
4
3
1
1
Host
Rat
46
28
11
Clonality (Clone)
Monoclonal ()
Conjugate
This NCR1 antibody is conjugated to APC
6
6
5
5
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
38
35
20
13
9
8
4
4
4
3
2
1
1
1
Options
Clone 29A1-4
Isotype IgG2a, kappa
Target
Alternative Name CD335 (NCR1 Antibody Abstract)
Background

Synonyms: Ly94,mAR-1,NK-p46,mNKp46,Lymphocyte antigen 94

Background: CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells, it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.

Gene ID 17086
UniProt Q8C567
Pathways Regulation of Leukocyte Mediated Immunity
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS with 0.05 % Proclin300, 1 % BSA
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.