IL17A antibody (Interleukin 17A) (APC)

Details for Product anti-IL17A Antibody No. ABIN6728586
Antigen
  • CTLA8
  • IL-17
  • IL-17A
  • IL17
  • Ctla-8
  • Ctla8
  • Il17
  • ChIL-17
  • IL-17F
  • IL17A
  • CTLA-8
  • interleukin 17A
  • IL17A
  • Il17a
Reactivity
Mouse (Murine)
163
83
34
4
4
3
3
2
2
2
Host
Rat
124
44
31
19
3
1
Clonality (Clone)
Monoclonal ()
Conjugate
This IL17A antibody is conjugated to APC
32
20
13
9
9
5
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
145
139
50
26
17
14
13
9
7
6
6
3
3
1
1
1
1
1
1
1
1
1
Options
Clone TC11-18H10-1
Isotype IgG1, kappa
Plasmids, Primers & others Plasmids, Primers & others IL17A products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name IL-17A (IL17A Antibody Abstract)
Background

Synonyms: Interleukin-17A,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8,CTLA8

Background: IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.

Gene ID 16171
UniProt Q62386
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS with 0.05 % Proclin300, 1 % BSA
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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