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MCM3 antibody (Minichromosome Maintenance Complex Component 3) (Cy3) Primary Antibody

MCM3 Reactivity: Human, Mouse, Rat IF (p) Host: Rabbit Polyclonal Cy3
Catalog No. ABIN676256
$442.20
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target
    MCM3
    Reactivity
    • 85
    • 40
    • 37
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 74
    • 10
    • 1
    Rabbit
    Clonality
    • 68
    • 17
    Polyclonal
    Conjugate
    • 46
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This MCM3 antibody is conjugated to Cy3
    Application
    • 59
    • 35
    • 21
    • 17
    • 13
    • 11
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MCM3
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 4°C
    Expiry Date
    12 months
  • Target
    MCM3
    Alternative Name
    Mcm3 (MCM3 Antibody Abstract)
    Synonyms
    CG4206, DmMCM3, DmMcm3, DmeMCM3, Dmel\\CG4206, MCM3, McM3, Mcp-PCR2, PCR2, dMCM3, cb32, chunp6867, wu:fa26g03, HCC5, P1-MCM3, P1.h, RLFB, xmcm3, AL033361, C80350, Mcmd, P1, p1.m, Minichromosome maintenance 3, minichromosome maintenance complex component 3, minichromosome maintenance complex component 3 L homeolog, Mcm3, MCM3, mcm3, mcm3.L
    Background

    MCM3 is one of the highly conserved mini-chromosome maintenance proteins that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.

    Synonyms: minichromosome maintenance deficient 3, Cervical cancer proto oncogene 5, DNA polymerase alpha holoenzyme associated P1, DNA polymerase alpha holoenzyme associated protein P1, DNA replication factor MCM3, DNA replication licensing factor MCM3, HCC 5, HCC5, hRlf beta subunit, Human cervical cancer proto oncogene 5, MCM 3, MCM3 minichromosome maintenance deficient 3, MGC1157, Minichromosome maintenance deficient 3, Minichromosome maintenance protein 3, P1 h, P1 MCM3, P1 Protein, P1.h, P102 protein, Replication licensing factor beta subunit, RLF beta subunit, RLF subunit beta, RLFB.

    Gene ID
    4172
    Pathways
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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