CACNA1G antibody (AA 901-1000)

Catalog No. ABIN680608

Product Details anti-CACNA1G Antibody

Target: CACNA1G (Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))

Binding Specificity: AA 901-1000

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA1G antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Possible cross-reactivity with CACNA1H and CACNA1I

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CACNA1G/Cav31

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CACNA1G antibody (ABIN680608)

Lu, Long, Zhou, Xu, Hu, Li: "Mibefradil reduces blood glucose concentration in db/db mice." in: Clinics (São Paulo, Brazil), Vol. 69, Issue 1, pp. 61-7, (2014) (PubMed).

Target Details for CACNA1G

Target: CACNA1G (Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))

Alternative Name: CACNA1G (CACNA1G Products)

Synonyms: CACNA1G antibody, cav3.1 antibody, ca(v)3.1 antibody, Ca(V)T.1 antibody, Cav3.1 antibody, NBR13 antibody, Cav3.1d antibody, [a]1G antibody, a1G antibody, alpha-1G antibody, mKIAA1123 antibody, Ca(v)3.1 antibody, calcium voltage-gated channel subunit alpha1 G antibody, calcium channel, voltage-dependent, T type, alpha 1G subunit antibody, calcium channel, voltage-dependent, T type, alpha 1G subunit L homeolog antibody, CACNA1G antibody, cacna1g antibody, cacna1g.L antibody, Cacna1g antibody

Background:

Synonyms: NBR13, Cav3.1, Ca(V)T.1, Voltage-dependent T-type calcium channel subunit alpha-1G, Cav3.1c, Voltage-gated calcium channel subunit alpha Cav3.1, CACNA1G, KIAA1123

Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil. A particularity of this type of channel is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

Gene ID: 8913

UniProt: O43497