TAF1 antibody (AA 501-600)

Catalog No. ABIN681073

Product Details anti-TAF1 Antibody

Target: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor (TAF1))

Binding Specificity: AA 501-600

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TBP Associated Factor 1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TAF1

Target: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor (TAF1))

Alternative Name: KAT4 (TAF1 Products)

Synonyms: 250kDa antibody, AU015687 antibody, B430306D02Rik antibody, Ccg-1 antibody, Ccg1 antibody, KAT4 antibody, N-TAF1 antibody, TAFII250 antibody, Taf2a antibody, BA2R antibody, CCG1 antibody, CCGS antibody, DYT3 antibody, DYT3/TAF1 antibody, NSCL2 antibody, OF antibody, P250 antibody, TAF2A antibody, XDP antibody, TATA-box binding protein associated factor 1 antibody, Taf1 antibody, TAF1 antibody

Background:

Synonyms: TBP Associated Factor 1, BA2R, CCG 1, CCG1, CCGS, Cell cycle G1 phase defect, Cell cycle gene 1 protein, Complementation of cell cycle block G1 to S, DYT3 protein, NSCL 2, NSCL2, OF, p250, TAF 1, TAF 2A, TAFII250, TAF1, TAF1 RNA polymerase II TATA box binding protein TBP associated factor 250 kDa, TAF1 RNA polymerase II TATA box binding protein TBP associated factor, TAF1 RNA polymerase II TATA box binding protein associated factor 250 kDa, TAF1_HUMAN, TAF2A, TAFII 250, TAFII-250, TAFII250, TAF II P250, TATA box binding protein TBP associated factor RNA polymerase II A, TATA box binding protein TBP associated factor RNA polymerase II A 250kD, TBP associated factor 250 kDa, TBP-associated factor 250 kDa, Transcription factor TFIID p250 polypeptide, Transcription initiation factor TFIID 250 kDa subunit, Transcription initiation factor TFIID subunit 1.

Background: Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle.

Gene ID: 6872