CD33 antibody (CD33 Molecule) (AA 90-130)

Details for Product anti-CD33 Antibody No. ABIN687607
Antigen
  • SIGLEC-3
  • SIGLEC3
  • p67
  • Siglec-3
  • gp67
  • CD33 molecule
  • CD33 antigen
  • CD33
  • Cd33
Epitope
AA 90-130
19
16
16
16
15
13
11
10
9
9
8
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
494
49
38
22
8
7
4
2
1
Host
Rabbit
369
147
1
1
1
Clonality
Polyclonal
Conjugate
This CD33 antibody is un-conjugated
60
53
36
23
12
10
7
6
6
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
328
193
120
105
88
52
28
25
24
19
18
17
12
6
6
5
3
2
2
1
Options
Immunogen KLH conjugated synthetic peptide derived from mouse CD33
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others CD33 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Cd33 (CD33 Antibody Abstract)
Background

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid (By similarity). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Subcellular location: Extracellular

Synonyms: gp67, Siglec-3, Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, CD33, Siglec3

Gene ID 12489
UniProt Q63994
Application Notes WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months
Supplier Images
Image no. 1 for anti-CD33 Molecule (CD33) (AA 90-130) antibody (ABIN687607) Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Rabbit Anti...
Image no. 2 for anti-CD33 Molecule (CD33) (AA 90-130) antibody (ABIN687607) Formalin-fixed and paraffin-embedded mouse intestine labeled with Anti-CD33/Siglec-3 ...
Image no. 3 for anti-CD33 Molecule (CD33) (AA 90-130) antibody (ABIN687607) Formalin-fixed and paraffin embedded mouse intestine labeled with Rabbit Anti CD33/Si...
Image no. 4 for anti-CD33 Molecule (CD33) (AA 90-130) antibody (ABIN687607) Lane 1: human colon carcinoma lysates Lane 2: rat lung lysates probed with Anti CD33 ...
Image no. 5 for anti-CD33 Molecule (CD33) (AA 90-130) antibody (ABIN687607) Mouse splenocytes probed with CD33 Polyclonal Antibody, Unconjugated at 1:100 for 30...
Image no. 6 for anti-CD33 Molecule (CD33) (AA 90-130) antibody (ABIN687607) Formalin-fixed and paraffin-embedded mouse intestine labeled with Anti-CD33/Siglec-3 ...
Product cited in: Shan, Bu, Zhang, Zhang, Ding, Chang, Dai, Shen, Ma: "LukS-PV, a component of Panton-Valentine leukocidin, exerts potent activity against acute myeloid leukemia in vitro and in vivo." in: The international journal of biochemistry & cell biology, Vol. 61C, pp. 20-28, 2015 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Mouse (Murine)). Further details: Sample: Liver

Iwami, Brinkman, Bromberg: "Vascular endothelial growth factor c/vascular endothelial growth factor receptor 3 signaling regulates chemokine gradients and lymphocyte migration from tissues to lymphatics." in: Transplantation, Vol. 99, Issue 4, pp. 668-77, 2015 (PubMed). Method employed by authors: Immunofluorescence (IF), Immunofluorescence (IF)

Jiang, Li, Shi, Wu, An, Yang, Xu: "Involvement of p38 in signal switching from autophagy to apoptosis via the PERK/eIF2α/ATF4 axis in selenite-treated NB4 cells." in: Cell death & disease, Vol. 5, pp. e1270, 2015 (PubMed). Method employed by authors: Immunohistochemistry (IHC)

Shi, Jiang, Li, Shan, Li, An, Yang, Xu: "Sodium selenite alters microtubule assembly and induces apoptosis in vitro and in vivo." in: Journal of hematology & oncology, Vol. 6, Issue 1, pp. 7, 2013 (PubMed). Method employed by authors: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Mouse (Murine)). Further details: Sample: spleen