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DNASE1L2 antibody (Deoxyribonuclease I-Like 2) (AA 200-250) (HRP) Primary Antibody

DNASE1L2 Reactivity: Human, Mouse, Rat IHC (p) Host: Rabbit Polyclonal HRP
Catalog No. ABIN6943056
$442.20
Plus shipping costs $45.00
100 μL
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  • Target
    DNASE1L2
    Binding Specificity
    AA 200-250
    • 14
    • 2
    • 2
    • 1
    • 1
    Reactivity
    Human, Mouse, Rat
    Host
    Rabbit
    • 22
    Clonality
    Polyclonal
    Conjugate
    This DNASE1L2 antibody is conjugated to HRP
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • 13
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DNASE1L2
    Isotype
    IgG
  • Application Notes
    IHC-P(1:200-400)
    Restrictions
    For Research Use only
  • Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
    Preservative
    Gentamicin sulfate
    Precaution of Use
    This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Expiry Date
    12 months
  • Target
    DNASE1L2
    Alternative Name
    DNASE1L2 (DNASE1L2 Antibody Abstract)
    Synonyms
    DNAS1L2, 4733401H14Rik, deoxyribonuclease 1 like 2, deoxyribonuclease 1-like 2, deoxyribonuclease-1-like 2, DNASE1L2, Dnase1l2, LOC100232225
    Background

    DNASE1L2 is a 299 amino acid secreted protein that is expressed in brain tissue and shares sequence similarity with DNase I, suggesting a possibly role in DNA hydrolysis. The gene encoding DNASE1L2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.


    Synonyms: Deoxyribonuclease I-like 2, Deoxyribonuclease-1-like 2, DNase I homolog protein DHP1, DNase I-like 2, Dnase1l2, DNSL2_HUMAN.
    Gene ID
    1775
    UniProt
    Q92874
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