DNASE1L2 antibody (Deoxyribonuclease I-Like 2) (AA 200-250) (Alexa Fluor 594)

Catalog No. ABIN6943062

Product Details anti-DNASE1L2 Antibody

Target:

DNASE1L2

Binding Specificity: AA 200-250

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNASE1L2 antibody is conjugated to Alexa Fluor 594

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNASE1L2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DNASE1L2

Target:

DNASE1L2

Alternative Name: DNASE1L2 (DNASE1L2 Antibody Abstract)

Synonyms: DNAS1L2, 4733401H14Rik, deoxyribonuclease 1 like 2, deoxyribonuclease 1-like 2, deoxyribonuclease-1-like 2, DNASE1L2, Dnase1l2, LOC100232225

Background:

DNASE1L2 is a 299 amino acid secreted protein that is expressed in brain tissue and shares sequence similarity with DNase I, suggesting a possibly role in DNA hydrolysis. The gene encoding DNASE1L2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Synonyms: Deoxyribonuclease I-like 2, Deoxyribonuclease-1-like 2, DNase I homolog protein DHP1, DNase I-like 2, Dnase1l2, DNSL2_HUMAN.

Gene ID: 1775

UniProt: Q92874