DNASE1L2 antibody (Deoxyribonuclease I-Like 2) (AA 200-250) (Alexa Fluor 594) Primary Antibody
DNASE1L2
Reactivity: Human, Mouse, Rat
IF (p)
Host: Rabbit
Polyclonal
Catalog No. ABIN6943062
$442.20
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100 μL
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- Target
- Binding Specificity
- AA 200-250
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Clonality
- Polyclonal
- Conjugate
- This DNASE1L2 antibody is conjugated to Alexa Fluor 594
- Application
- Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human DNASE1L2
- Isotype
- IgG
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- Application Notes
- IF(IHC-P)(1:50-200)
- Restrictions
- For Research Use only
-
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
-
- Target
- Alternative Name
- DNASE1L2 (DNASE1L2 Antibody Abstract)
- Synonyms
- DNAS1L2, 4733401H14Rik, deoxyribonuclease 1 like 2, deoxyribonuclease 1-like 2, deoxyribonuclease-1-like 2, DNASE1L2, Dnase1l2, LOC100232225
- Background
DNASE1L2 is a 299 amino acid secreted protein that is expressed in brain tissue and shares sequence similarity with DNase I, suggesting a possibly role in DNA hydrolysis. The gene encoding DNASE1L2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Synonyms: Deoxyribonuclease I-like 2, Deoxyribonuclease-1-like 2, DNase I homolog protein DHP1, DNase I-like 2, Dnase1l2, DNSL2_HUMAN.- Gene ID
- 1775
- UniProt
- Q92874
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