NFKBIE antibody (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon)

Details for Product anti-NFKBIE Antibody No. ABIN6944283
Antigen
  • NFKBIE
  • IKBE
  • Slc35b2
  • NFKB inhibitor epsilon
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
  • nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
  • NFKBIE
  • Nfkbie
Reactivity
Human
147
93
59
7
2
2
2
1
1
1
Host
Rabbit
149
2
Clonality (Clone)
Monoclonal ()
Conjugate
This NFKBIE antibody is un-conjugated
7
7
7
7
7
7
7
3
3
3
3
3
3
3
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
81
51
39
26
22
11
6
2
2
Options
Immunogen Full length protein
Clone 7A4
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others NFKBIE products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name NFKBIE (NFKBIE Antibody Abstract)
Background

The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.


Synonyms: NF-kappa-B inhibitor epsilon, I-kappa-B-epsilon, NF-kappa-BIE, IkB-E, IkB-epsilon, IKB epsilon, IkappaBepsilon, NFKBIE, NFKB inhibitor epsilon
Gene ID 4794
UniProt O00221
Pathways NF-kappaB Signaling, Maintenance of Protein Location
Application Notes WB(1:500-1000), IHC-P(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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