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ORC2 antibody

ORC2 Reactivity: Human WB, IF (cc) Host: Mouse Monoclonal 5C3 unconjugated
Catalog No. ABIN6944371
  • Target See all ORC2 Antibodies
    ORC2 (Origin Recognition Complex Subunit 2 (ORC2))
    Reactivity
    • 27
    • 19
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 37
    • 4
    • 1
    Mouse
    Clonality
    • 37
    • 5
    Monoclonal
    Conjugate
    • 23
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ORC2 antibody is un-conjugated
    Application
    • 27
    • 15
    • 13
    • 13
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
    Cross-Reactivity
    Human
    Purification
    Protein G purified monoclonal antibody in PBS containing 0.05% azide.
    Immunogen
    Monoclonal antibody raised in mouse against human ORC2, using two recombinant proteins containing the N-terminal and C-terminal part of the protein, respectively
    Clone
    5C3
    Isotype
    IgG1
    Top Product
    Discover our top product ORC2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 μg/μL
    Buffer
    PBS with 0.05 % sodium azide.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    ORC2 (Origin Recognition Complex Subunit 2 (ORC2))
    Alternative Name
    ORC2 (ORC2 Products)
    Background

    Synonyms: ORC2L, Origin recognition complex subunit 2, ORC2

    Background: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3.

    Gene ID
    4999
    UniProt
    Q13416
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