ORC2 antibody

Details for Product No. ABIN6944371
Antigen
  • CG3041
  • DmORC 2
  • DmORC2
  • DmOrc2
  • DmOrc2p
  • Dmel\\CG3041
  • ORC
  • ORC2
  • Orc-2
  • Orc2p
  • fs(3)293
  • fs(3)293-19
  • k43
  • l(3)88Ab
  • l(3)A5
  • l(3)K43
  • l(3)SG44
  • l(3)dsl5
  • l(3)k43
  • orc2
  • rDmORC
  • ATORC2
  • F13M22.6
  • F13M22_6
  • ORIGIN RECOGNITION COMPLEX SECOND LARGEST SUBUNIT 2
  • origin recognition complex second largest subunit 2
  • ORC2L
  • AU041563
  • Orc2l
  • orc2-a
  • orc2l
  • xorc2
  • Origin recognition complex subunit 2
  • origin recognition complex second largest subunit 2
  • origin recognition complex subunit 2
  • origin recognition complex, subunit 2
  • origin recognition complex subunit 2 S homeolog
  • Orc2
  • ORC2
  • orc2.S
  • orc-2
Reactivity
Human
62
11
11
4
2
1
1
1
1
1
Host
Mouse
49
9
4
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
2
2
2
2
2
1
1
1
1
1
1
Application
Western Blotting (WB)
55
26
10
6
6
5
3
1
1
Options
Immunogen Monoclonal antibody raised in mouse against human ORC2, using two recombinant proteins containing the N-terminal and C-terminal part of the protein, respectively
Clone 5C3
Isotype IgG1
Purification Protein G purified monoclonal antibody in PBS containing 0.05% azide.
Antigen
Background

Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3.


Synonyms: ORC2L, Origin recognition complex subunit 2, ORC2
Gene ID 4999
UniProt Q13416
Application Notes WB(1:300-1000)
Restrictions For Research Use only
Concentration 0.6 μg/μL
Storage -20 °C
Storage Comment Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
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