ORC2 antibody
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- Target See all ORC2 Antibodies
- ORC2 (Origin Recognition Complex Subunit 2 (ORC2))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ORC2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Human
- Purification
- Protein G purified monoclonal antibody in PBS containing 0.05% azide.
- Immunogen
- Monoclonal antibody raised in mouse against human ORC2, using two recombinant proteins containing the N-terminal and C-terminal part of the protein, respectively
- Clone
- 5C3
- Isotype
- IgG1
- Top Product
- Discover our top product ORC2 Primary Antibody
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- Application Notes
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WB 1:300-5000
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.6 μg/μL
- Buffer
- PBS with 0.05 % sodium azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- ORC2 (Origin Recognition Complex Subunit 2 (ORC2))
- Alternative Name
- ORC2 (ORC2 Products)
- Background
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Synonyms: ORC2L, Origin recognition complex subunit 2, ORC2
Background: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3.
- Gene ID
- 4999
- UniProt
- Q13416
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