ARPC5 antibody (Actin Related Protein 2/3 Complex, Subunit 5, 16kDa)

Details for Product anti-ARPC5 Antibody No. ABIN6944379
Antigen
  • arc16
  • p16-arc
  • ARPC5
  • APOBEC4
  • ARC16
  • dJ127C7.3
  • p16-Arc
  • MGC86407
  • 5830443F10Rik
  • actin related protein 2/3 complex subunit 5
  • actin related protein 2/3 complex subunit 5 L homeolog
  • actin related protein 2/3 complex, subunit 5
  • actin related protein 2/3 complex, subunit 5B
  • ARPC5
  • arpc5
  • arpc5.L
  • Arpc5
  • arpc5b
Reactivity
Human, Mouse (Murine), Rat (Rattus)
56
39
39
2
2
1
1
1
1
Host
Rabbit
50
6
Clonality (Clone)
Monoclonal ()
Conjugate
This ARPC5 antibody is un-conjugated
3
3
3
3
3
3
3
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (IHC), Western Blotting (WB)
29
13
11
8
4
3
3
2
2
2
1
Options
Immunogen Recombinant human p16 ARC around N-terminus
Clone 8D8
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others ARPC5 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name p16 ARC (ARPC5 Antibody Abstract)
Background

Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).


Synonyms: Actin-related protein 2/3 complex subunit 5, Arp2/3 complex 16 kDa subunit, p16-ARC, ARPC5
Gene ID 10092
UniProt O15511
Pathways RTK Signaling, Regulation of Actin Filament Polymerization
Application Notes WB(1:300-1000), FCM(1:20-100), IF(ICC)(1:50-200), IHC()
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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