PLIN1 antibody (Perilipin 1) (AA 350-400) (Biotin)

Details for Product anti-PLIN1 Antibody No. ABIN6944483
Target
Binding Specificity
AA 350-400
15
12
9
8
5
4
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse, Rat
83
53
44
10
8
6
4
2
2
2
2
2
1
1
Host
Rabbit
68
8
8
8
1
Clonality
Polyclonal
Conjugate
This PLIN1 antibody is conjugated to Biotin
8
6
4
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
64
23
15
13
13
8
6
6
4
3
1
1
Options
Immunogen KLH conjugated synthetic peptide derived from human IFNAR2
Isotype IgG
Purification Purified by Protein A.
Target
Alternative Name Perilipin 1 (PLIN1 Antibody Abstract)
Background

Perilipins, members of the PAT protein family (named after lipid droplet proteins Perilipin, Adipophilin, and TIP47) are found exclusively at the surface of lipid droplets in adipocytes and steroidogenic cells. They have been suggested to function as regulators of lipolysis and triacylglycerol storage within adipose tissue. Four distinct isoforms ranging from perilipin A (57 kDa) to perilipin D (26 kDa) have been identified and they share an identical amino terminal sequences, and contain 2-6 consensus protein kinase A (PKA) phosphorylation sites. Perilipin C and D have been detected only in steroidogenic cells. Perilipin A is the most abundant form on the lipid droplets of adipocytes. The phosphorylation of perilipin by PKA, which is accompanied by the phosphorylation and translocation of hormone-sensitive lipase from the cytosol to the lipid droplets, promotes lipolysis. There is evidence for the presence of perilipin A in atheroma plaques suggesting that the protein may be involved in the development of therosclerosis by controlling as in adipocytes the hydrolysis of stored lipids.


Synonyms: Lipid droplet associated protein, Lipid droplet-associated protein, PERI, Perilipin, Perilipin-1, Perilipin 1, PerilipinA, Perilipin-A, PLIN, PLIN1, PLIN1_HUMAN.
Gene ID 5346
UniProt O60240
Pathways Lipid Metabolism
Application Notes WB(1:500-2000)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months