POSTN antibody (Periostin, Osteoblast Specific Factor)

Details for Product anti-POSTN Antibody No. ABIN6944485
Antigen
  • fa99h07
  • pn
  • postn
  • wu:fa99h07
  • wu:fc70f09
  • zgc:153873
  • LOC100008945
  • osf-2
  • pdlpostn
  • periostin
  • OSF-2
  • OSF2
  • PDLPOSTN
  • PN
  • RP11-412K4.1
  • A630052E07Rik
  • AI747096
  • Osf2
  • PLF
  • peri
  • Plf
  • periostin
  • periostin, osteoblast specific factor b
  • periostin, osteoblast specific factor
  • POSTN
  • postnb
  • postn
  • Postn
Reactivity
Human
144
87
54
12
6
4
3
3
3
3
3
3
2
2
2
1
1
Host
Rabbit
147
26
10
4
3
Clonality (Clone)
Monoclonal ()
Conjugate
This POSTN antibody is un-conjugated
23
10
6
3
3
3
3
3
3
3
3
3
Application
Flow Cytometry (FACS), Western Blotting (WB)
153
77
70
21
20
17
13
7
5
3
2
2
2
1
Options
Immunogen Human Perilipin-1 aa 400 to the C-terminus
Clone 2F7
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others POSTN products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Periostin (POSTN Antibody Abstract)
Background

Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide-linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for alpha(V)beta and alpha(V)beta integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor β 1(TGF β 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.


Synonyms: Periostin, Osteoblast-specific factor 2, PN, OSF-2, POSTN, OSF2, PDLPOSTN.
Gene ID 10631
UniProt Q15063
Application Notes WB(1:500-2000), FCM(1:50-100)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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