PEX5 antibody (Peroxisomal Biogenesis Factor 5) (AA 70-120) (Cy3)

Details for Product anti-PEX5 Antibody No. ABIN6944513
Antigen
  • AW212715
  • ESTM1
  • PTS1R
  • Pxr1
  • X83306
  • PTS1-BP
  • PBD2A
  • PBD2B
  • PXR1
  • Peroxin-5
  • peroxisomal biogenesis factor 5
  • pex5
  • Pex5
  • PEX5
Epitope
AA 70-120
44
4
3
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
96
75
71
7
4
4
3
3
3
2
1
Host
Rabbit
85
10
1
Clonality
Polyclonal
Conjugate
This PEX5 antibody is conjugated to Cy3
5
4
4
4
4
4
4
4
3
3
3
3
3
3
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
42
38
16
15
14
11
3
2
1
1
Options
Immunogen KLH conjugated synthetic peptide derived from human PEX5
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others PEX5 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name PEX5 (PEX5 Antibody Abstract)
Background

The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]


Synonyms: FLJ50634, FLJ50721, FLJ51948, Peroxin 5, Peroxin-5, Peroxisomal biogenesis factor 5, Peroxisomal C terminal targeting signal import receptor, Peroxisomal C-terminal targeting signal import receptor, Peroxisomal targeting signal 1 receptor, Peroxisome receptor 1, pex5, PEX5_HUMAN, PTS1 BP, PTS1 receptor, PTS1-BP, PTS1R, PXR1.
Gene ID 5830
UniProt P50542
Pathways Monocarboxylic Acid Catabolic Process
Application Notes IF(IHC-P)(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Expiry Date 12 months
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