SMARCA5 antibody (AA 901-1000)

Catalog No. ABIN6944964

Product Details anti-SMARCA5 Antibody

Target: SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5))

Binding Specificity: AA 901-1000

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMARCA5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Specificity: Possible cross-reactivity with SMARCA1/SNF2L1

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SNF2H

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SMARCA5

Target: SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5))

Alternative Name: SNF2H (SMARCA5 Products)

Background:

Synonyms: 4933427E24Rik, ATP-dependent chromatin remodeling protein SNF2H, D030040M08Rik, D330027N15Rik, EC 3.6.1.-, hISWI, hSNF2H, ISWI, MommeD4, SMARCA5, SMCA5, SMCA5_HUMAN, Snf2h, Sucrose nonfermenting like 5, Sucrose nonfermenting protein 2 homolog, Sucrose nonfermenting, yeast, homolog of, sucrose nonfermenting-like 5, SWI/SNF related matrix associated actin dependent regulator of chromatin a5, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily a member 5, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5, WCRF135.

Background: The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. [provided by RefSeq, Jul 2008]

Gene ID: 8476

UniProt: O60264

Pathways: Chromatin Binding