Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) antibody Primary Antibody
MLL1
Reactivity: Human
ChIP-seq, ChIP, ELISA
Host: Rabbit
Polyclonal
Catalog No. ABIN6952424
$550.50
Plus shipping costs $45.00
100 μL
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-
- Target
- Reactivity
- Human
- Host
- Rabbit
- Clonality
- Polyclonal
- Conjugate
- Un-conjugated
- Application
- ChIP DNA-Sequencing (ChIP-seq), Chromatin Immunoprecipitation (ChIP), ELISA
- Specificity
- Polyclonal antibody raised in rabbit against human MLL1 (Mixed-Lineage Leukemia) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.
- Purification
- whole antiserum
- Grade
- ChIP-seq Grade
- Immunogen
- synthetic peptide
-
-
- Application Notes
- ChIP/ChIP-seq 2 μL:ChIP
ELISA 1:100 - 1:1,000 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- serum, 0.05 % azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
-
- Target
- Alternative Name
- MLL1 (MLL1 Antibody Abstract)
- Synonyms
- Mll, Mll1, 6430520K01, ALL-1, All1, Cxxc7, HRX, HTRX1, mKIAA4050, lysine methyltransferase 2A, lysine (K)-specific methyltransferase 2A, Kmt2a
- Background
- MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.
- UniProt
- Q03164
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