PPP6R3 antibody (AA 151-250) (AbBy Fluor® 594)

Catalog No. ABIN6979337

Product Details anti-PPP6R3 Antibody (AbBy Fluor® 594)

Target: PPP6R3 (Protein Phosphatase 6, Regulatory Subunit 3 (PPP6R3))

Binding Specificity: AA 151-250

Reactivity: Human, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP6R3 antibody is conjugated to AbBy Fluor® 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Hamster, Human

Predicted Reactivity: Mouse,Rat,Dog,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SAPS3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PPP6R3

Target: PPP6R3 (Protein Phosphatase 6, Regulatory Subunit 3 (PPP6R3))

Alternative Name: SAPS3 (PPP6R3 Products)

Background:

Synonyms: C11orf23, Chromosome 11 open reading frame 23, KIAA1558, PP6R3, PP6R3_HUMAN, PPP6R3, Protein phosphatase 6 regulatory subunit 3, SAP190, SAPL, SAPLa, SAPS domain family member 3, SAPS domain family, member 3, Serine/threonine-protein phosphatase 6 regulatory subunit 3, Sporulation induced transcript 4 associated protein SAPL, Sporulation-induced transcript 4-associated protein SAPL.

Background: Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C, MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010]

Gene ID: 55291

UniProt: Q5H9R7