RASSF10 antibody (N-Term)

Catalog No. ABIN6991539

Product Details anti-RASSF10 Antibody

Target: RASSF10 (Ras Association (RalGDS/AF-6) Domain Family (N-Terminal) Member 10 (RASSF10))

Binding Specificity: AA 50-100, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASSF10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: RASSF10 antibody will not cross-react with other RAS association domain-containing family members.

Purification: RASSF10 Antibody is affinity chromatography purified via peptide column.

Immunogen: RASSF10 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human RASSF10. The immunogen is located within amino acids 50 - 100 of RASSF10.

Isotype: IgG

Application Details

Application Notes: RASSF10 antibody can be used for detection of RASSF10 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: RASSF10 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: RASSF10 antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for RASSF10

Target: RASSF10 (Ras Association (RalGDS/AF-6) Domain Family (N-Terminal) Member 10 (RASSF10))

Alternative Name: RASSF10 (RASSF10 Products)

Synonyms: 4632411J06Rik antibody, Ras association domain family member 10 antibody, Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 antibody, RASSF10 antibody, Rassf10 antibody

Background: RASSF10 Antibody: RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains. While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival.

Gene ID: 644943

NCBI Accession: NP_001073990

UniProt: A6NK89