BATF antibody (N-Term)

Catalog No. ABIN6991768

Product Details anti-BATF Antibody

Target: BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BATF antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Specificity: Multiple isoforms of BATF are known to exist. Despite its predicted molecular weight, BATF often migrates at a higher than expected molecular weight.

Purification: BATF Antibody is affinity chromatography purified via peptide column.

Immunogen: BATF antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BATF. The immunogen is located within the first 50 amino acids of BATF.

Isotype: IgG

Application Details

Application Notes: BATF antibody can be used for detection of BATF by Western blot at 0.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: BATF Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: BATF antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for BATF

Target: BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))

Alternative Name: BATF (BATF Products)

Background: BATF Antibody: BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.

Molecular Weight: 14 kDa

Gene ID: 10538

NCBI Accession: NP_006390

UniProt: Q16520