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MBP antibody

Reactivity: Rat, Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7249818
  • Target See all MBP products
    MBP
    Reactivity
    • 57
    • 41
    • 38
    • 4
    • 3
    Rat, Mouse
    Host
    • 53
    • 8
    • 2
    Rabbit
    Clonality
    • 50
    • 13
    Polyclonal
    Conjugate
    • 21
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This MBP antibody is un-conjugated
    Application
    • 34
    • 29
    • 26
    • 26
    • 22
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Mouse Myelin Basic Protein
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:1000, IHC 1:200-1:600
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    300 μg/mL
    Buffer
    PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MBP
    Abstract
    MBP Products
    Synonyms
    C76307 antibody, Hmbpr antibody, R75289 antibody, golli-mbp antibody, mld antibody, shi antibody, Mbps antibody, cb274 antibody, fj33b11 antibody, mbp antibody, wu:fj33b11 antibody, wu:fq15b02 antibody, zgc:136630 antibody, myelin basic protein antibody, myelin basic protein a antibody, MBP antibody, Mbp antibody, mbpa antibody
    Background
    MBP belongs to the myelin basic protein family. The classic group of MBP isoforms (isoform 4-isoform 14) are the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. MBP has six isoforms. Catalog#10458-1-AP is capable of recognizing multiple isoforms of MBP.
    Molecular Weight

    Observed_MW: 17-22 kDa

    Calculated_MW: 17-22 kDa

    UniProt
    P04370, P02688
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