TGFBR2 antibody

Catalog No. ABIN7251268

Product Details anti-TGFBR2 Antibody

Target: TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGFBR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthesized peptide derived from the Internal region of human TGFbeta RII

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TGFBR2

Target: TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))

Alternative Name: TGF beta Receptor II (TGFBR2 Products)

Background: TGFBR2 (Transforming Growth Factor BetaReceptor2) is a Protein Coding gene. Diseases associated withTGFBR2 includeLoeys-Dietz Syndrome 2andEsophageal Cancer. Among its related pathways areSMAD2/3 MH2 Domain Mutants in CancerandExtracellular vesicle-mediated signaling in recipient cells. GO annotations related to this gene includetransferase activity, transferring phosphorus-containing groupsandprotein tyrosine kinase activity. An important paralog of this gene isACVR2B.

Molecular Weight:

Observed_MW: 65 kDa

Calculated_MW: 65 kDa

UniProt: P37173