FNDC3B antibody
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- Target See all FNDC3B Antibodies
- FNDC3B (Fibronectin Type III Domain Containing 3B (FNDC3B))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FNDC3B antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogen
- Full length fusion protein
- Isotype
- IgG
- Top Product
- Discover our top product FNDC3B Primary Antibody
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anti-Fibronectin Type III Domain Containing 3B (FNDC3B) (AA 5-71) antibody
FNDC3B Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Fibronectin Type III Domain Containing 3B (FNDC3B) (AA 176-205), (N-Term) antibodyFNDC3B Reactivity: Human WB Host: Rabbit Polyclonal RB23415 unconjugated
anti-Fibronectin Type III Domain Containing 3B (FNDC3B) (AA 250-299) antibodyFNDC3B Reactivity: Human, Dog, Horse, Rabbit, Bat WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IHC 1:30-1:150, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.8 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- FNDC3B (Fibronectin Type III Domain Containing 3B (FNDC3B))
- Alternative Name
- FNDC3B (FNDC3B Products)
- Background
- Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.
- UniProt
- Q53EP0
- Pathways
- Positive Regulation of fat Cell Differentiation
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