SUSD2 antibody (PE)

Catalog No. ABIN7013898

Product Details anti-SUSD2 Antibody

Target: SUSD2 (Sushi Domain Containing 2 (SUSD2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SUSD2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: The mouse monoclonal antibody W5C5 recognizes an extracellular epitope of SUSD2, a type I transmembrane protein expressed on mesenchymal stem-like cells. This antibody selectively binds to a MSCs in both bone marrow and endometrium or tonsil, and can be used for their identification and isolation.

Purification: The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.

Immunogen: WERI-RB-1 retinoblastoma cells

Clone: W5C5

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.

Target Details for SUSD2

Target: SUSD2 (Sushi Domain Containing 2 (SUSD2))

Alternative Name: SUSD2 (SUSD2 Products)

Synonyms: BK65A6.2 antibody, 1200011D11Rik antibody, sushi domain containing 2 antibody, SUSD2 antibody, Susd2 antibody

Background:

NCBI Full Gene Name: sushi domain containing 2

Description: SUSD2 (sushi domain containing protein 2) is a type I transmembrane protein, that serves as an important marker of bone marrow-derived mesenchymal stem-like cells (bone marrow stromal cells). These pluripotent cells are important for techniques of autologous cell therapy, and can be collected from e.g. endometrium, or palatine tonsil. SUSD2 seems to be a tumor supresor, and is down-regulated in colon cancer tissues, whereas it is highly expressed e.g. in breast cancer.

Gene ID: 56241

UniProt: Q9UGT4