MC4R antibody (Extracellular, N-Term)

Catalog No. ABIN7043324

Product Details anti-MC4R Antibody

Target: MC4R (Melanocortin 4 Receptor (MC4R))

Binding Specificity: AA 6-20, Extracellular, N-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC4R antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Live Cell Imaging (LCI)

Characteristics: Anti-MC4 Receptor (extracellular) Antibody (ABIN7043324, ABIN7044596 and ABIN7044597)) is a highly specific antibody directed against an epitope of the human melanocortin receptor 4. The antibody can be used in western blot, immunohistochemistry, and immunocytochemistry applications. It recognizes an extracellular epitope and can potentially recognize the receptor in living cells. It has been designed to recognize MC4R from human, mouse, and rat samples.

Purification: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)HRGMHTSLHLWNRSS, corresponding to amino acid residues 6-20 of human MC4R

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.8 mg/mL

Buffer: Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1 % BSA, 0.05 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Target Details for MC4R

Target: MC4R (Melanocortin 4 Receptor (MC4R))

Alternative Name: MC4 Receptor (MC4R Products)

Background: Alternative names: MC4 Receptor, Melanocortin receptor 4, MC4R, MC4-R

Gene ID: 4160

NCBI Accession: NM_005912

UniProt: P32245

Pathways: Hormone Transport, cAMP Metabolic Process, Feeding Behaviour