RYR1 antibody (Intracellular, N-Term)

Catalog No. ABIN7043604

Product Details anti-RYR1 Antibody

Target: RYR1 (Ryanodine Receptor 1 (Skeletal) (RYR1))

Binding Specificity: AA 1371-1386, Intracellular, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RYR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Characteristics: Anti-Ryanodine Receptor 1 Antibody (ABIN7043604, ABIN7045211 and ABIN7045212)) is a highly specific antibody directed against an epitope of human RyR1. The antibody can be used in western blot, immunocytochemistry, and immunohistochemistry applications. It has been designed to recognize RyR1 from human, rat, and mouse samples.

Purification: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)RAENEKDATTEKNKKR, corresponding to amino acid residues 1371-1386 of human RyR1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.8 mg/mL

Buffer: Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1 % BSA, 0.05 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Target Details for RYR1

Target: RYR1 (Ryanodine Receptor 1 (Skeletal) (RYR1))

Alternative Name: Ryanodine Receptor 1 (RYR1 Products)

Background: Alternative names: Ryanodine Receptor 1, RyR1, Skeletal muscle-type ryanodine receptor

Gene ID: 6261

NCBI Accession: NM_000540

UniProt: P21817

Pathways: Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development