TSH receptor antibody (Extracellular, N-Term)

Catalog No. ABIN7043810

Product Details anti-TSH receptor Antibody

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Binding Specificity: AA 376-390, Extracellular, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSH receptor antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Anti-TSH Receptor (TSHR) (extracellular) Antibody (ABIN7043810, ABIN7045322 and ABIN7045323)) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot analysis. The antibody recognizes an extracellular epitope and thus is ideal for detecting the receptor in living cells. It has been designed to recognize TSHR from human, rat, and mouse samples.

Purification: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: ETLQAFDSHYDYTVC, corresponding to amino acid residues 376-390 of rat TSHR

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.85 mg/mL

Buffer: Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1 % BSA, 0.05 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Target Details for TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Alternative Name: TSH Receptor (TSHR) (TSHR Products)

Background: Alternative names: TSH Receptor (TSHR), Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-R

Gene ID: 25360

NCBI Accession: NM_000369

UniProt: P21463

Pathways: Thyroid Hormone Synthesis