ISR-alpha antibody
-
- Target See all ISR-alpha Antibodies
- ISR-alpha (Insulin Receptor alpha (ISR-alpha))
-
Reactivity
- Human, Rat, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This ISR-alpha antibody is un-conjugated
-
Application
- Immunofluorescence (IF), Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Rat
- Purification
- Affinity purification
- Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse Insulin Receptor alpha
-
-
- Application Notes
-
IHC: 1: 3000-1: 6000
Human, Mouse, Rat: Human, Mouse, Rat
Positive Tissue: endometrial cancer, esophagus cancer, uterus,small intestine - Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
-
- Target
- ISR-alpha (Insulin Receptor alpha (ISR-alpha))
- Alternative Name
- Insulin Receptor alpha (ISR-alpha Products)
- Background
- This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.
- Gene ID
- 16337
- UniProt
- P15208
-