Thymopoietin antibody

Catalog No. ABIN7091741

Product Details anti-Thymopoietin Antibody

Target: Thymopoietin (TMPO)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Thymopoietin antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Human

Immunogen: Recombinant human LAP2.

Clone: A2D12

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Thymopoietin

Target: Thymopoietin (TMPO)

Alternative Name: TMPO (TMPO Products)

Background:

Synonyms: LAP2, LAP2A_HUMAN, Isoforms beta/gamma, Lamina associated polypeptide 2 alpha, Lamina associated polypeptide 2, Thymopoietin, Thymopoietin isoform alpha, TP alpha, TP, LAP2-alpha, LAP2 alpha.

Background: Lamins are type V intermediate filament proteins and are grouped into constitutively expressed B-type lamins and developmentally regulated A-type lamins. Lamin-binding proteins in the nuclear lamina and the nuclear interior include several protein families and/or types of proteins in higher eukaryotes such as the inner nuclear membrane proteins, lamin B receptor, emerin, MANI, three isoforms of lamina-associated polypeptide 1 (LAP 1), and several isoforms of LAP 2. Up to six LAP 2 isoforms derive from a single gene by alternative splicing in mammals and various isoforms have been described in Xenopus. The best characterized LAP2 isoforms are the inner nuclear membrane protein LAP 2 beta and the nucleoplasmic protein LAP 2 alpha, which are identical in their N-terminal 187-amino acid constant region but differ in their C termini. LAP 2 alpha specifically interacts with A-type lamins within the nuclear interior as part of a detergent- and salt-resistant nucleoskeletal structure.

Gene ID: 7112

UniProt: Q96RT1