CD133 Antigen (AA 836-865) antibody (Biotin)

Catalog No. ABIN7091859

Product Details

Target: CD133 Antigen

Binding Specificity: AA 836-865

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Fruit Fly

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD133 antigen

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details

Target: CD133 Antigen

Background:

Synonyms: AC133, Antigen AC133, Hematopoietic stem cell antigen, hProminin, PROM1, Prominin I, Prominin like protein 1 precursor, Prominin mouse like 1, prominin1, PROML1, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4, PROM1_HUMAN.

Background: Binds cholesterol in cholesterol-containing plasma membrane microdomains. Proposed to play a role in apical plasma membrane organization of epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

Gene ID: 8842

UniProt: O43490