PGC antibody
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- Target See all PGC Antibodies
- PGC (Pepsinogen C (PGC))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PGC antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- Antigen affinity purification
- Immunogen
- Fusion protein of Human PGC
- Isotype
- IgG
- Top Product
- Discover our top product PGC Primary Antibody
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- Application Notes
- ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PGC (Pepsinogen C (PGC))
- Alternative Name
- PGC (PGC Products)
- Background
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Background: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
Aliases: Gastricsin antibody, PEPC antibody, PEPC_HUMAN antibody, pepsin C antibody, Pepsinogen C antibody, pepsinogen group II antibody, PGC antibody, PGII antibody, preprogastricsin antibody, Progastricsin antibody
- UniProt
- P20142
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